Protein Modification Reagents

eMolecules​ 557756-85-1 | FMOC-NH-PEG4-CH2CH2COOH | AstaTech | MFCD06656472 | 487.549 | C26H33NO8 | 95.000 | OC(=O)CCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 1g | 302808807

FMOC-NH-PEG4-CH2CH2COOH | AstaTech | 557756-85-1 | MFCD06656472 | 487.549 | C26H33NO8 | 95.000 | OC(=O)CCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 1g | 302808807

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Medchemexpress LLC Mal-PEG2-oxyamine | 1146245-73-9 | 95.0% | C10H16N2O5 | 10MG

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Mal-PEG2-oxyamine is a bifunctional PEG-based linker for use in the synthesis of PROTACs. It features a maleimide group and an aminooxy (oxyamine) group connected by a short PEG2 spacer, permitting orthogonal conjugation to thiol and carbonyl functionalities for targeted protein degradation research. The product is supplied with a reported purity of 95% and includes storage and solubility guidance for research applications.

• Bifunctional maleimide and aminooxy reactive groups.
• PEG2 spacer provides a short, flexible linkage.
• Enables selective conjugation to thiol and carbonyl partners.
• Reported purity supports synthetic and analytical use.
• Includes storage and solubility recommendations for stability.

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Medchemexpress LLC (S,R,S)-AHPC-PEG2-N3 | 2010159-45-0 | 99.9% | 601.72 g/mol | C28H39N7O6S | 5 MG

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(S,R,S)-AHPC-PEG2-N3 is an E3 ligase ligand-linker conjugate bearing a terminal azide for click chemistry, used as a building block in PROTAC synthesis and bioconjugation.

• Terminal azide enables copper-catalyzed and strain-promoted azide-alkyne cycloaddition.
• Two-unit PEG linker provides solubility and spacer functionality.
• Designed for conjugation to alkyne, DBCO, or BCN functional partners.
• Supplied in small-quantity formats for research and synthesis workflows.
• Molecular weight 601.72 g/mol; molecular formula C28H39N7O6S.

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eMolecules​ 123502-57-8 | Bis-PEG11-NHS ester | Broadpharm | MFCD30527397 | 796.817 | C34H56N2O19 | 95.000 | O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 500mg | 340377030

Bis-PEG11-NHS ester | Broadpharm | 123502-57-8 | MFCD30527397 | 796.817 | C34H56N2O19 | 95.000 | O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 500mg | 340377030

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Creative Pegworks PEG-G-PEI PEG 5K PEI 25K PEG/P

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PEG-g-PEI , PEG 5k, PEI 25k, PEG/PEI ratio 30

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Nanocs THIOL PEG BIOTIN, HS-PEG-BIOTI

Thiol PEG Biotin, HS-PEG-Biotin, 600 Da, 100 mg

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Medchemexpress LLC Mal-PEG8-Phe-Lys-PAB-Exatecan TFA | 98.7% | 1548.58 | 5 MG

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Mal-PEG8-Phe-Lys-PAB-Exatecan TFA is an agent-linker conjugate for antibody-drug conjugates (ADC), composed of the degradable linker Mal-PEG8-Phe-Lys-PAB and the toxin molecule Exatecan. This agent is intended for research use only.

• Composed of degradable linker Mal-PEG8-Phe-Lys-PAB
• Contains toxin molecule Exatecan
• Carries a highly potent small-molecule toxin
• Targets specific antigens of tumor cell surfaces with high binding affinity
• Internalized into tumor cells and digested in lysosome to release antitumor toxin

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eMolecules​ 1807512-47-5 | Mal-PEG2-PFP | Broadpharm | MFCD26127799 | 423.292 | C17H14F5NO6 | 98.000 | Fc1c(F)c(F)c(OC(=O)CCOCCOCCN2C(=O)C=CC2=O)c(F)c1F | 100mg | 229582671

Mal-PEG2-PFP | Broadpharm | 1807512-47-5 | MFCD26127799 | 423.292 | C17H14F5NO6 | 98.000 | Fc1c(F)c(F)c(OC(=O)CCOCCOCCN2C(=O)C=CC2=O)c(F)c1F | 100mg | 229582671

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Medchemexpress LLC Propargyl-PEG4-NHS ester | 1428629-70-2 | MFCD22380743 | 97.0% | 357.36 g/mol | C16H23NO8 | 250 MG

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Propargyl-PEG4-NHS ester is a noncleavable four-unit polyethylene glycol (PEG) linker bearing a propargyl (alkyne) group and an N-hydroxysuccinimide (NHS) ester. It is used as a click chemistry reagent to couple azide-containing molecules via copper-catalyzed azide-alkyne cycloaddition (CuAAC), and as a PEG-based linker in antibody-drug conjugate synthesis and other bioconjugation applications.

• Noncleavable four-unit PEG linker provides a hydrophilic spacer.
• Terminal propargyl (alkyne) group enables copper-catalyzed azide-alkyne click chemistry.
• NHS ester is amine-reactive for efficient conjugation to primary amines.
• High purity (97.0%) and molecular weight of 357.36 g/mol aid predictable performance.
• Viscous liquid form; recommended storage: pure form -20°C, in solvent -80°C or -20°C.

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Life Diagnostics Inc Human Anti-PEG IgM ELISA

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Human Anti-PEG IgM ELISA

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Medchemexpress LLC Cl-C6-PEG4-O-CH2COOH | 1799506-30-1 | 98.0% | 370.87 | 1 G

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Cl-C6-PEG4-O-CH2COOH is a PEG-based PROTAC linker designed for the synthesis of chloroalkane-containing PROTACs (HaloPROTACs). This linker facilitates the formation of PROTACs, which are molecules that leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

• PEG-based PROTAC linker.
• Used in the synthesis of chloroalkane-containing PROTACs (HaloPROTACs).
• Facilitates PROTACs with two ligands for E3 ubiquitin ligase and target protein.
• Exploits the intracellular ubiquitin-proteasome system.
• Selectively degrades target proteins.

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Cayman Chemical PomalIdomIde 4alkylC6amIn 50mg

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A PROTAC building block; has been used in the synthesis of PROTACs that drive HDAC8 degradation

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Medchemexpress LLC Azide-PEG4-VC-PAB-doxorubicin | 99.6% | 1222.25 g/mol | C57H75N9O21 | 10 MG

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Azide-PEG4-VC-PAB-doxorubicin is a drug-linker conjugate used in antibody-drug conjugate research and click-chemistry bioconjugation.

• Contains an azide functional group for click chemistry.
• Valine-citrulline peptide linker with a PAB self-immolative spacer.
• Molecular weight 1222.25 g/mol.
• Chemical formula C57H75N9O21.
• Purity 99.6%.
• Pack size includes 10 mg solid and other sizes.
• Appearance orange to red solid.
• Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).

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eMolecules​ Cy5-PEG5-NHBoc | BroadpharmMFCD28142459 | 881.590 | C49H73ClN4O8 | 96.000 | [Cl-].CN1\C(=C\C=C\C=C\C2=[N+](CCCCCC(=O)NCCOCCOCCOCCOCCOCCNC(=O)OC(C)(C)C)c3ccccc3C2(C)C)C(C)(C)c2ccccc12 | 10mg | 263744685

Cy5-PEG5-NHBoc | BroadpharmMFCD28142459 | 881.590 | C49H73ClN4O8 | 96.000 | [Cl-].CN1\C(=C\C=C\C=C\C2=[N+](CCCCCC(=O)NCCOCCOCCOCCOCCOCCNC(=O)OC(C)(C)C)c3ccccc3C2(C)C)C(C)(C)c2ccccc12 | 10mg | 263744685

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Chemscene ChemScene | N-Boc-PEG6-alcohol | 1G | CS-0091656 | 0.97 | 331242-61-6| MFCD28385472 | 381.46

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ChemScene | N-Boc-PEG6-alcohol | 1G | CS-0091656 | 0.97 | 331242-61-6| MFCD28385472 | 381.46

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